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Application of titanium-based artificial heart thrombus

Application of titanium-based artificial heart thrombus - "Tantalum membrane improves the thrombosis resistance of titanium-based artificial heart"

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Figure 1 (A) Thrombosis around the heart valve frame and struts. (B) Fibrin formation. (C) Fibrin forms a thrombus.

 

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Figure 2 Schematic diagram of medical device-related thrombosis

The initial protein adsorption on the implant surface mediates all subsequent phenomena.

 

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Figure 3 Adhesion and activation of platelets on the surface of biomaterials

 

 

 

Table 1 Hemocompatibility test

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Fig. 4 Optical images of platelet aggregation on steel surfaces with different coatings 

(a) initial titanium, (b) tantalum, (c) tantalum oxide, d) tantalum nitride, (e) tantalum oxynitride


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 Fig.5 AFM images of platelet aggregation on steel surfaces with different coatings

(a) initial titanium, (b) tantalum, (c) tantalum oxide, d) tantalum nitride, (e) tantalum oxynitride